MATRIX METALLOPROTEINASES: KEY PLAYERS IN TISSUE REMODELING AND DISEASE

Matrix metalloproteinases MMPs (MMPs) represent a large family of zinc-dependent endopeptidases. These proteases play critical functions in {extracellular matrix remodeling, contributing to physiological processes such as wound healing, embryogenesis, and angiogenesis. However, dysregulation of MMP activity is correlated to a wide variety of pathol